[Application of denaturing high performance liquid chromatography to mutation detection of the c-kit gene in mastocytosis].

@article{Zhang2006ApplicationOD,
  title={[Application of denaturing high performance liquid chromatography to mutation detection of the c-kit gene in mastocytosis].},
  author={Ling-yan Zhang and G Xu and Nicholas C. P. Cross},
  journal={Zhongguo shi yan xue ye xue za zhi},
  year={2006},
  volume={14 5},
  pages={981-4}
}
The aim of study was to detect mutation of tyrosine domain of c-kit gene in mastocytosis using denaturing high performance liquid chromatography technique, and to investigate the significance of this gene mutation in diagnosis and therapy of mastocytosis. Genomic DNA was obtained from bone marrow or peripheral blood leukocytes using the phenol/chloroform… CONTINUE READING