[Application of combined chromosome karyotype analysis and multiplex ligation probe amplification technique for the prenatal diagnosis of fetal abnormalities].

OBJECTIVE To assess the value of combined chromosome karyotype analysis and multiplex ligation probe amplification (MLPA) assay for the prenatal diagnosis of fetuses with abnormalities detected by ultrasonography. METHODS With informed consent obtained, 72 pregnant women with ultrasound detected fetal structural abnormalities underwent percutaneous… CONTINUE READING