[Apoptosis-inducing effect of alternol on mouse lymphocyte leukemia cells and its mechanism].

@article{Liu2007ApoptosisinducingEO,
  title={[Apoptosis-inducing effect of alternol on mouse lymphocyte leukemia cells and its mechanism].},
  author={Zhao-zhe Liu and Jie-peng Chen and Su-lan Zhao and Chang-ling Li},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  year={2007},
  volume={42 12},
  pages={1259-65}
}
Alternol is purified from fermentation productions of microorganisms named as Alternaria alternata var. monosporus. The research is to investigate the apoptosis-inducing effect of alternol on mouse lymphocyte leukemia (L1210) cells and the possible mechanisms. MTT method was used to evaluate the viability of L1210 cells. Apoptosis of L1210 cells was detected by morphological assessment, DNA electrophoresis assay and flow cytometry. Western blotting analysis was carried out to determine the… CONTINUE READING
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