[Antisense oligonucleotides with pharmacologic action].

  title={[Antisense oligonucleotides with pharmacologic action].},
  author={Roxana-Georgiana Tauşer and Ortansa Stoica},
  journal={Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi},
  volume={107 1},
The potential therapeutic applications of the antisense strategy are illustrated by numerous examples of the oligonucleotides investigated in preclinical and clinical trials especially for antiviral, antiinflammatory, anticancer and antiatherosclerotic activity. The main advantages of the antisense oligonucleotides therapeutic candidates are comparatively discussed with the classical drugs.