[Antisense oligonucleotides targeting protein kinase C alpha inhibits the proliferation of A549 cells].

OBJECTIVE To investigate the effects of antisense oligonucleotides (ASODN) targeting protein kinase C alpha (PKCalpha) on the proliferation of A549 cells. METHODS PKCalpha ASODN and random oligonucleotides (RODN) were transfected into A549 cells mediated by polyethyleneimine, and the proliferation and clone formation of A549 cells were detected by CCK-8… (More)