[Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations].

@article{Tincani2010AntiphospholipidAL,
  title={[Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations].},
  author={Angela Tincani and Cinzia Casu and Stefania Cartella and Tamara Ziglioli and Roberto Cattaneo},
  journal={Reumatismo},
  year={2010},
  volume={62 1},
  pages={65-75}
}
Antiphospholipid antibodies (aPL) represent a heterogeneous group of antibodies that recognize various antigenic targets including beta2 glycoprotein I (beta2GPI), prothrombin (PT), activated protein C, tissue plasminogen activator, plasmin and annexin A2. The most commonly used tests to detect aPL are: lupus anticoagulant (LAC), a functional coagulation assay, anticardiolipin antibody (aCL) and anti-beta2GPI antibody (anti-beta2GPI), which are enzyme-linked immunoassay (ELISA). Clinically aPL… CONTINUE READING
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