[Antinuclear antibodies].

  title={[Antinuclear antibodies].},
  author={Claire Goulvestre},
  journal={Presse medicale},
  volume={35 2 Pt 2},
Antinuclear antibodies react with various nuclear autoantigens. Testing for them is critical for diagnosing connective tissue diseases, but they may be also found in other inflammatory diseases and in the elderly. They constitute a group of heterogeneous autoantibodies, and their specificity helps to discriminate between various connective tissue diseases. Screening for total antinuclear antibodies is generally performed by indirect immunofluorescence on HEp2 cells. In the presence of… CONTINUE READING