[Antineutrophil cytoplasmic autoantibodies in systemic vasculitis].

  title={[Antineutrophil cytoplasmic autoantibodies in systemic vasculitis].},
  author={Jostein Skjalg Hagemo and Knut Ivar Aasar\od and Torolf Moen},
  journal={Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke},
  volume={122 12},
BACKGROUND Antineutrophil cytoplasmic autoantibodies (ANCA) are directed against antigens located in the cytoplasm of neutrophil granulocytes and monocytes. Detection of ANCA has proved to be a useful diagnostic tool for a group of systemic vasculitis, especially Wegener's granulomatosis. Both indirect immunofluorescence (IIF) and ELISA have been used to detect ANCA. MATERIAL AND METHODS In this study, samples from 319 patients tested by both immunofluorescence and ELISA were evaluated; 27 of… CONTINUE READING


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