[Antimalarial drug resistance].

  title={[Antimalarial drug resistance].},
  author={Jacques Le bras and Lise Musset and J{\'e}r{\^o}me Clain},
  journal={Medecine et maladies infectieuses},
  volume={36 8},
Drug resistant malaria is mostly due to Plasmodium falciparum, the highly prevalent species in tropical Africa, Amazon, and Southeast Asia. P. falciparum is responsible for severe involvement of fever or anemia causing more than a million deaths per year. Rationale for treatment is becoming weak as multiple drug resistance against well-tolerated drugs develops. P. falciparum drug resistant malaria originates from chromosomal mutations. Analyses using molecular, genetic and biochemical… CONTINUE READING