Corpus ID: 23440218

[Antigenic preparations from Opisthorchis and their use in immunodiagnosis. 2. The effectiveness of antibody detection in infected patients].

@article{Teplukhin1990AntigenicPF,
  title={[Antigenic preparations from Opisthorchis and their use in immunodiagnosis. 2. The effectiveness of antibody detection in infected patients].},
  author={Iu V Teplukhin and B. V. Karal'nik and Iu A Kuz'min and L. Gorbunova},
  journal={Meditsinskaia parazitologiia i parazitarnye bolezni},
  year={1990},
  volume={4},
  pages={
          46-8
        }
}
Serological studies using opisthorchis immunoreagents of various specificity (metabolic, somatic and from eggs) have shown that metabolic antigen preparations were the most effective. Simultaneous use of 3 immunoreagents of various specificity ensures higher percentage of opisthorchiasis patients' identification. Passive hemagglutination test and enzyme immunoassay are practically identically effective for the antibody determination. 
1 Citations
Development of an ELISA using anti-idiotypic antibody for diagnosis of opisthorchiasis.
TLDR
Examination of human sera by this ELISA compared with commercial assays demonstrated that the monoclonal antibody epitope is located within this significant parasite protein, indicating substitution of parasite antigen with anti-idiotype avoids the use of experimental animals and also reduces time-consuming steps of antigen preparation. Expand