[Antidepressant and tolerance: Determinants and management of major side effects].

@article{David2016AntidepressantAT,
  title={[Antidepressant and tolerance: Determinants and management of major side effects].},
  author={Denis J David and David Gourion},
  journal={L'Encephale},
  year={2016},
  volume={42 6},
  pages={553-561}
}
Antidepressant therapy aims to reach remission of depressive symptoms while reducing the complications and risks of relapse. Even though they have proven their efficacy, it takes several weeks for antidepressants to demonstrate full effectiveness, and adverse effects occur more quickly or (quicker) which can be a source of poor compliance. This latest aspect often leads to dose reduction and/or change of molecule that have the effect of delaying remission. This review attempts to present, from… CONTINUE READING