Corpus ID: 12469726

[Anti-inflammatory effect of ACTH in the rat].

@article{Seghaye1986AntiinflammatoryEO,
  title={[Anti-inflammatory effect of ACTH in the rat].},
  author={R Seghaye and E. Deflandre and G. Remacle-Volon and Jacques Damas},
  journal={Comptes rendus des seances de la Societe de biologie et de ses filiales},
  year={1986},
  volume={180 3},
  pages={
          379-85
        }
}
In rats, ACTH reduced the oedemas induced by zymosan and lambda carrageenan. ACTH reduced the volume of the exudate induced by sponge implantation and its content in proteins, beta-galactosidase, beta-glucuronidase and PGE2. The inhibitory effect of ACTH was suppressed by adrenalectomy which increased the carrageenan-oedema. The inhibitory effect of ACTH was also suppressed by 17 alpha-methyltestosterone. Corticosterone reduced carrageenan-oedema. The inhibitory effect of corticosterone was… Expand
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