[Anti-inflammatory activity of 21-methyl-20,21-diketocorticosteroids. II. Anti-inflammatory activity of 11 beta,17 alpha-dihydroxy-21-methylpregna-1,4-diene-3,20,21-trione 17-acetate(TSC-5) (author's transl)].

@article{Kuzuna1979AntiinflammatoryAO,
  title={[Anti-inflammatory activity of 21-methyl-20,21-diketocorticosteroids. II. Anti-inflammatory activity of 11 beta,17 alpha-dihydroxy-21-methylpregna-1,4-diene-3,20,21-trione 17-acetate(TSC-5) (author's transl)].},
  author={Seiji Kuzuna and Mikihiko Obayashi and Shigeru Morimoto and Kiyohisa Kawai},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  year={1979},
  volume={99 9},
  pages={
          871-9
        }
}
  • S. Kuzuna, M. Obayashi, K. Kawai
  • Published 1 September 1979
  • Medicine
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
1 Citations

Anti‐Inflammatory Glucocorticoids

TLDR
The discovery of selective receptor modulators, which maintain beneficial therapeutic activity together with a diminished risk of side effects, focuses on ligands that lead to repression rather than activation of genes targeted by the glucocorticoid receptor.