[Anti-Mullerian hormone. Structure and role in sexual differentiation].

  title={[Anti-Mullerian hormone. Structure and role in sexual differentiation].},
  author={T Jarmińska-Jackowiak and Alina Warenik-Szymankiewicz and Wiesław H. Trzeciak},
  journal={Ginekologia polska},
  volume={66 1},
Anti-müllerian hormone (AMH) which plays a key role in male sexual differentiation is a glycoprotein, produced by Sertoli cells. In male fetuses AMH is responsible for regression of Müllerian duct, the analgen of uterus, the Fallopian tubes, and 2/3 upper of the vagina, while in female fetuses for a decrease in aromatase activity in granulosa cells of the ovary. Human AMH gene consists of 5 exons: 412, 124, 108, 160 and 856 bp in length, and is localized near the tip of chromosome 19, in… CONTINUE READING