[Angiotensin and arteriosclerosis: an approach from transgenic and knockout mice].


This brief review was designed to summarize the relationship between the renin-angiotensin system and arteriosclerosis. Tsukuba hypertensive mice (THM) carrying both the human renin and angiotensinogen genes and C57BL/6J control mice 2 to 3 months of age were fed with either a western or normal diet for 14 weeks. Compared with controls, microscopic analyses… (More)


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