[Angelman syndrome--the research model of epigenetic mechanisms expression genes regulation].

@article{SzpechtPotocka2009AngelmanSR,
  title={[Angelman syndrome--the research model of epigenetic mechanisms expression genes regulation].},
  author={Agnieszka Szpecht-Potocka and Monika Gos and Radosław Struniawski and Jerzy Bal},
  journal={Medycyna wieku rozwojowego},
  year={2009},
  volume={13 2},
  pages={123-30}
}
Epigenetics, one of the widely investigated topics in human genetics, refers to phenotypic or gene expression changes caused by specific regulatory mechanisms (eg. DNA methylation, histone proteins modifications, antisense RNA or RNAi expression) that do not involve changes in DNA sequence. The disturbances in epigenetic gene expression regulatory mechanisms might lead to oncogenic transformation as well as monogenic or complex diseases. On the other side, better knowledge about epigenetic… CONTINUE READING