[Androgen receptor gene mutations in prostate cancer].

  title={[Androgen receptor gene mutations in prostate cancer].},
  author={Charlie Kiat Meng Wang and Toyoaki Uchida},
  journal={Nihon Hinyokika Gakkai zasshi. The japanese journal of urology},
  volume={88 5},
PURPOSE Androgens are required for the development of normal prostate and prostate cancer, through their action via the androgen receptor (AR). Although prostate cancer is potentially curable in the early stages by radical prostatectomy, androgen ablation is standard treatment for metastatic prostate cancer. Metastatic prostate cancer is incurable despite temporary remission commonly achieved by androgen ablation therapy. To investigate the mechanism for the development of human prostate cancer… CONTINUE READING
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