[Analysis of the adverse effects of drugs at the cellular and subcellular levels].

Abstract

A release of histamine after the lipophilic betablockers exaprolol and propranolol correlates with their capability of displacing the bound membrane Ca2+ and increasing the disorder of phospholipidic membranes of the isolated mast cells. Electron microscopy confirmed intracellular displacement of histamine from granules of mast cells after exaprolol without… (More)

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@article{Nosl1990AnalysisOT, title={[Analysis of the adverse effects of drugs at the cellular and subcellular levels].}, author={Rado Nos{\'a}l' and Katar{\'i}na Dr{\'a}bikov{\'a} and Jana Pe{\vc}ivov{\'a} and Karol Ondrias and J{\'a}n Jakubovsk{\'y}}, journal={Ceskoslovenska farmacie}, year={1990}, volume={39 3}, pages={118-21} }