[Analysis of sperm chromosomal abnormalities and sperm DNA fragmentation in infertile males].

@article{Qiu2008AnalysisOS,
  title={[Analysis of sperm chromosomal abnormalities and sperm DNA fragmentation in infertile males].},
  author={Yueling Qiu and Leiguang Wang and Lihong Zhang and Dantong Yang and Aidong Zhang and Jianchun Yu},
  journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics},
  year={2008},
  volume={25 6},
  pages={
          681-5
        }
}
OBJECTIVE To investigate changes in sperm chromosome and sperm DNA integrity of infertile males. METHODS The level of DNA fragmentation was determined by Sperm Chromatin Dispersion (SCD) test in infertile males with idiopathic severe oligoasthenozoospermia (ISOA, n= 19), couples with unexplained recurrent miscarriage (URM, n= 38) and adult healthy fertile men (control group, n= 32). Multi-color fluorescence in situ hybridization (FISH) was performed with probes specific for chromosomes 13, 18… CONTINUE READING

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