[Analysis of de novo copy number variations in a family affected with autism spectrum disorders using high-resolution array-based comparative genomic hybridization].

@article{He2012AnalysisOD,
  title={[Analysis of de novo copy number variations in a family affected with autism spectrum disorders using high-resolution array-based comparative genomic hybridization].},
  author={Wen-zhi He and Wei-qiang Liu and Xin-qi Zhong and Xiao-lin Chen and Shao-ying Li and Hui-min Zhang and Qing Li and Qi-liang Cui and Xiaofang Sun},
  journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics},
  year={2012},
  volume={29 3},
  pages={266-9}
}
OBJECTIVE To analyze de novo copy number variations (CNVs) in a Chinese family affected with autism spectrum disorders (ASD). METHODS Affymetrix Cytogenetics Whole Genome 2.7M Array assay was performed to identify potential CNVs in four members from the family. RESULTS A total of 89 de novo CNV regions were identified in the autistic siblings. The CNV… CONTINUE READING