[An improved BALB/c 3T3 cell transformation assay and its application in the cocarcinogenesis study].

Abstract

OBJECTIVE To improve the protocol of BALB/c 3T3 cell transformation assay, and apply it to the cocarcinogenesis study. METHOD Appropriate serum concentration, culture media and method of administration were selected by testing their effects on the growth and transformation of BALB/c 3T3 cells. The co-carcinogenic activity between diethylnitrosamine (DEN… (More)

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