[An history of the CRISPR-Cas systems discovery].

@article{Pourcel2017AnHO,
  title={[An history of the CRISPR-Cas systems discovery].},
  author={Christine Pourcel},
  journal={Biologie aujourd'hui},
  year={2017},
  volume={211 4},
  pages={
          247-254
        }
}
From 1987 and during the following 20 years, a few research teams exploring bacteria and archea genome sequences uncover the prokaryotic adaptative immune system made of the CRISPR sequence and associated cas genes. First believed to be similar to the eukaryote RNA interference system, CRISPR-Cas turned out to be unique and of an amazing genetic complexity… CONTINUE READING