[An expression analysis of miR-200a in serum and liver tissue during the process of liver cancer development in rats].

@article{Xia2014AnEA,
  title={[An expression analysis of miR-200a in serum and liver tissue during the process of liver cancer development in rats].},
  author={Ning Shao Xia and Yuan Gao and Xiaoxia Wang and Weihui Liu and Jiandong Yang and Tao Wang and G G Zhao and Haimin Li},
  journal={Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology},
  year={2014},
  volume={22 6},
  pages={440-4}
}
OBJECTIVE To explore whether microRNA-200a (miR-200a) could be used as a novel biomarker of liver cancer using a rat model system. METHODS Diethylnitrosamine abdominal injection was applied to induce liver cancer in the F344 rat strain (n =40); ten unmodeled rats served as controls. In addition, human subjects with normal healthy liver (n =10), liver cirrhosis (n =10), and liver cancer (n =10) were enrolled in the study. Blood samples from both rats and patients and rats' livers were… CONTINUE READING