[An experimental study on the regulation of the expression of Th2 cytokines by nuclear factor-kappaB and protein kinase C in asthma].


OBJECTIVE To explore the role of nuclear factor-kappaB (NF-kappaB) in the signal pathway of protein kinase C (PKC) regulating the expression of Th2 cytokines, interleukin 4 (IL-4) and IL-5, by T lymphocyte in asthma. METHODS 16 guinea pigs were randomly divided into 2 groups, normal control and asthmatic group. 16 asthmatic patients and 16 normal control… (More)


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