[Altered effective connectivity of insula in nicotine addiction].

  title={[Altered effective connectivity of insula in nicotine addiction].},
  author={Wu Yang and Feng Wang and Zhen Zhang and Xiang Ren and Zhiyuan Zhang and Yang Li and Tao Sun},
  journal={Zhonghua yi xue za zhi},
  volume={94 21},
OBJECTIVE To explore the changes of effective connectivity associated with insula in different nicotine addiction sessions so as to understand its role and function. METHODS A total of 20 smokers received the scans of resting-state functional magnetic resonance imaging in two sessions of different conditions: smoking abstinence followed by smoking satiety. Group ICA was initially adopted to obtain the independent component patterns. And paired t-test of ICA spatial patterns revealed such… CONTINUE READING

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