[Alpha-synuclein in Parkinson's disease].

  title={[Alpha-synuclein in Parkinson's disease].},
  author={Anna Oczkowska and Wojciech Kozubski and Jolanta Dorszewska},
  journal={Przeglad lekarski},
  volume={71 1},
Parkinson's disease (PD) is a degenerative disease of the central nervous system, of which patomechanizm entirely is not clear. In the picture neuropathologically there is observed degeneration and loss of dopaminergic neurons, but also noradrenergic, serotonergic and cholinergic neurons in patients with PD. It is believed, that causes of PD are both environmental and genetic factors, associated mainly with mutations in the SNCA and PRKN genes, which may lead to changes in the structure of… CONTINUE READING


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