Corpus ID: 6612886

[Alpha lipoic acid affect the function of EPCs incubated by high-glucose].

@article{Chen2012AlphaLA,
  title={[Alpha lipoic acid affect the function of EPCs incubated by high-glucose].},
  author={Shu-chun Chen and G. Song and Dong-mei Zhang and N. Liu},
  journal={Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology},
  year={2012},
  volume={28 3},
  pages={
          240-3
        }
}
  • Shu-chun Chen, G. Song, +1 author N. Liu
  • Published 2012
  • Biology, Medicine
  • Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
AIM EPCs were cultured in high-glucose-medium to induce oxidative stress. Concentration of malonaldehyde (MDA) and nitrogen monoxidum (NO) in culture medium were measured. The function of EPCs and protein expression of GPx-1 and eNOS were determined. Antioxidant alpha lipoic acid (ALA) was used as an intervention factor to explore the mechanism by which glucose induces the damage of EPCs. METHODS EPCs were isolated and cultured from 15 Wistar rats (180-200 g). After planted for 4 days and 24… Expand