[Allogeneic stem cell transplantation in the management of acute myeloid leukemia].

@article{Schmid2007AllogeneicSC,
  title={[Allogeneic stem cell transplantation in the management of acute myeloid leukemia].},
  author={Christoph Schmid and H U Kolb},
  journal={Medizinische Klinik},
  year={2007},
  volume={102 4},
  pages={317-23}
}
Allogeneic stem cell transplantation (SCT) is the most powerful treatment option for acute myeloid leukemia (AML). However, SCT is also complicated by a high risk for treatment-related morbidity and mortality. The antileukemic effect of SCT is based on the radio-/chemotherapy applied for conditioning, as well as on the allogeneic immune reaction, mediated by immunocompetent donor cells, the graft-versus-leukemia effect. The latter effect is of particular importance in the context of reduced… CONTINUE READING