[Advances on the profiling of 5-hydroxymethylcytosine].

Abstract

5-hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. Accumulating studies have revealed the essential role of 5hmC in embryonic development, brain function and cancer research. Compared to another well-known cytosine methylation derivate, 5-methylcytosine (5mC), the detection of… (More)
DOI: 10.16288/j.yczz.15-480

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