[Adenovirus-mediated double suicide gene selectively kills breast cancer MCF-7 cells in vitro].

OBJECTIVE To evaluate the effect of adenovirus-mediated double suicide gene (CD/TK) for selective killing of breast cancer cells. METHODS Vascular endothelial growth factor (VEGF)-expressing MCF-7 cells and normal human mammary epithelial cells that did not express VEGF were infected with the adenovirus containing VEGFP-CD/TK-GFP genes. CD/TK gene… CONTINUE READING