[Acute pharmacokinetics of the Tl+ ion in the rabbit. 3-compartment model].

New Zealand rabbits were used to determine the acute kinetics of the Tl+ ion (0 to 90 minutes) following intravenous administration of two doses of Tl+ (10 mg.kg-1 and 30 mg.kg-1). The rapid disappearance of Tl+ from the blood may be explained by means of an open parallel tricompartmental mamillary model. The most important pharmacokinetic parameters which… CONTINUE READING