[Acute myeloid Leukemia].

  • Jan Braess
  • Published 1993 in Deutsche medizinische Wochenschrift


Acute myeloid leukemia (AML) has been genetically characterized extensively and can now be subdivided into 9 to 11 pathogenetically different subtypes according to their profile of driver mutations. In clinical practice karyotyping and molecular analysis of NPM1, cEBPa and FLT3-ITD are required for treatment stratification and potentially genotype specific… (More)


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