[Acute effects of IL-1β on sodium current in cortical neurons of rats].

@article{Qi2011AcuteEO,
  title={[Acute effects of IL-1β on sodium current in cortical neurons of rats].},
  author={Cui Qi and Wei-Wei Zhang and Fei Wang and Chao-Fei Bao and Xinwei Wang and Xiao-Nan Li and Xiao-Qing Yu and Chen Zhou},
  journal={Dong wu xue yan jiu = Zoological research},
  year={2011},
  volume={32 3},
  pages={323-8}
}
Interleukin-1β (IL-1β) is an important proinflammatory cytokine that plays a key role in injuries and diseases of the central nervous system (CNS). The voltage-gated Na(+) channel is the most important ion channel of neurons, and is essential for regenerative action potential (AP). The Na(+) channel also contributes to many diseases of the brain. However, relations between IL-1β and central Na(+) channels remain unreported. In this study, whole cell patch-clamp recording was used to investigate… CONTINUE READING