[Activation of the complement system in different forms of glomerulonephritis].

  title={[Activation of the complement system in different forms of glomerulonephritis].},
  author={Edgar Wegm{\"u}ller and Brigitte M. Frey and J. E. Hodler},
  journal={Schweizerische medizinische Wochenschrift},
  volume={107 29},
The complement system may be activated by two pathways, the classical and the alternate. To evaluate their respective participation in different forms of glomerulonephritis, the plasma values of C3, C4, C3PA, C1q and properdin were determined in 70 patients. In systemic lupus erythematosus (LED), acute poststreptococcal glomerulonephritis (AGN) and septicemia the classical pathway appears to be mainly involved, whereas the amplification loop and the alternate pathway seem to be of secondary… CONTINUE READING