author={Philippe Berbis},
  journal={Annales de dermatologie et de venereologie},
  volume={128 6-7},
  • Philippe Berbis
  • Published 2001 in Annales de dermatologie et de venereologie
Acitretin (Soriatane(R)) is an aromatic retinoïd (carboxylic acid metabolite of etretinate). Acitretin has a terminal elimination half-life of about 55 to 60 hours. However, concomitant intake of alcohol induces transformation to etretinate (lipophilic ester) which has a longer terminal elimination half life (84 to 168 days). Due to the teratogenic effect… CONTINUE READING