[Absence of T lymphocyte functions in athymic nude rats (author's transl)].


Immunological characterization of nude rats (rnu/rnu) of outbred hooded stock was attempted. Antibody responses of IgM and IgG classes against thymus-dependent antigen, sheep red blood cells (SRBC), were detected in heterozygous (+/rnu) rats but were totally lacking in homozygous (rnu/rnu) nude rats. When mouse Sarcoma 180 was transplanted, tumor cells were… (More)