[Abolition of hypotension following spinal anaesthesia by dihydroergotamine (DHE) (author's transl)].

@article{Zimpfer1979AbolitionOH,
  title={[Abolition of hypotension following spinal anaesthesia by dihydroergotamine (DHE) (author's transl)].},
  author={Michael Zimpfer and Sylvia Fitzal and Laszlo Tonczar},
  journal={Der Anaesthesist},
  year={1979},
  volume={28 4},
  pages={43-7}
}
The conduction block of the preganglionic sympathetic fibres in spina anaesthesia leads to peripheral vasodilation. Such a loss of tone in blood vessels is also pronounced on the venous side. Therefore the effects of intravenously administered DHE (10 microgram/kg i.v.) on 25 healthy patients undergoing spinal anaesthesia were studied. Though all patients were preinfused with 500 ml Ringer there was a sustained decrease in arterial and pulmonary artery pressures (p less than 0.001). However… CONTINUE READING