[ADP-ribosylation of nuclear proteins in the rat brain].

  title={[ADP-ribosylation of nuclear proteins in the rat brain].},
  author={T M Zaalishvili and K M Kolkhidashvili and D O Margiani and R D Michilashvili},
  volume={53 6},
The distribution of (ADP-ribose)n synthesized from [14C]NAD labeled at the adenyl ring in several protein fractions of isolated rat brain nuclei was studied. Preferential ADP-ribosylation of nonhistone nuclear proteins was shown to occur. It was demonstrated that pol (ADP-ribose)polymerase and DNA-topoisomerase II are located spatially close to each other… CONTINUE READING