[ABP: the testicular protein that binds androgens].

  title={[ABP: the testicular protein that binds androgens].},
  author={Michel Courot},
  journal={Reproduction, nutrition, developpement},
  volume={20 2},
  • Michel Courot
  • Published in Reproduction, nutrition, developpement 1980
ABP is a protein found in the testicular cytosol or secreted by Sertoli cells in the rete testis fluid. It has a high affinity for androgers and binds specifically 5 alpha-DHT and testosterone (but to a lesser extent). The binding capacity is saturable. ABP is measured by steady state polyacrylamide gel electrophoresis or by separation on dextran coated charcoal. ABP moves from testis to epididymis where its binding activity is totally or partially destroyed from caput to cauda epididymis. In… CONTINUE READING