[ABL1, SRC and other non-receptor protein tyrosine kinases as new targets for specific anticancer therapy].

Abstract

Non-receptor protein tyrosine kinases are responsible for signal transduction during many physiologic cellular processes, including cell growth and proliferation, apoptosis, differentiation, regulation of actin cytoskeleton, cell shape, adhesion, motility and migration. Aberrant activity of protein tyrosine kinases (acquired as a result of chromosomal… (More)

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