[A study in the Ivory Coast (1985-1987) of the efficacy and tolerance of ivermectin (Mectizan) in human onchocerciasis. I. A comparative double-blind study of 220 patients with onchocerciasis treated with a single oral dose of 100, 150 or 200 mcg/kg].

@article{Lariviere1989ASI,
  title={[A study in the Ivory Coast (1985-1987) of the efficacy and tolerance of ivermectin (Mectizan) in human onchocerciasis. I. A comparative double-blind study of 220 patients with onchocerciasis treated with a single oral dose of 100, 150 or 200 mcg/kg].},
  author={M J Lariviere and B Beauvais and Mohamed Aziz and J F Garin and Johan V S Abeloos and Francis Derouin and Masahiro Bamba and C Bossebceuf and M Ferly-Therizol and Claudine Sarfati},
  journal={Bulletin de la Societe de pathologie exotique et de ses filiales},
  year={1989},
  volume={82 1},
  pages={35-47}
}
Two hundred and twenty adult males living in endemic onchocerciasis areas in Ivory Coast, with a mean of 59 to 64 mf/mg of skin microfilariae, having or not ocular lesions, were divided into 4 homogeneous groups and treated by placebo or by a single oral dose of 100, 150 or 200 mcg/kg of ivermectin. Parasitological, clinical, ophthalmological, biological data were gathered before treatment (J less than 1) and at day 4 and 3, 6, 12 months post treatment. The doses of 150 to 200 mcg/kg gave the… CONTINUE READING