• Medicine
  • Published in
    Gan to kagaku ryoho. Cancer…
    1996

[A randomized controlled study of maintenance therapy with (2"R)-4'-O-tetrahydropyranyladriamycin for advanced and recurrent breast cancer. Clinical Study Group of THP for Breast Cancer in Japan].

@article{Enomoto1996ARC,
  title={[A randomized controlled study of maintenance therapy with (2"R)-4'-O-tetrahydropyranyladriamycin for advanced and recurrent breast cancer. Clinical Study Group of THP for Breast Cancer in Japan].},
  author={Kohji Enomoto and Takeshi Tominaga and Rikiya Abe and Yuichi Iino and Hiroo Koyama and Yasuo Nomura and Osahiko Abe and Hiroaki Nakazato},
  journal={Gan to kagaku ryoho. Cancer & chemotherapy},
  year={1996},
  volume={23 7},
  pages={
          871-80
        }
}
We conducted a randomized controlled study to evaluate the clinical usefulness of (2"R) -4'-O-Tetrahydropyranyladriamycin (THP)-based combination therapy subsequent to induction therapy which was consisted with THP, 5'-DFUR, and CPA in the treatment of advanced or recurrent breast cancer. In maintenance therapy, Arm C received CPA and TAM, and Arm T received these two drugs plus THP. Survival time of 50% for all cases in which maintenance therapy was conducted was 26.9 months in Arm T and 20.9… CONTINUE READING