[A prospective investigation on interferon treatment of chronic hepatitis B].

@article{Liu1998API,
  title={[A prospective investigation on interferon treatment of chronic hepatitis B].},
  author={Guo-zhen Liu and Guodong Hu and De-ming Tan and Zhen-gang Zhang},
  journal={Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University},
  year={1998},
  volume={23 4},
  pages={400-2}
}
Mismatched polymerase chain reaction and restriction fragment length polymorphism assay together with neutralization bioassay were performed in order to elucidate the influence of pre core mutation of HBV genome and neutralizing anti-INF on the therapeutic efficacy of IFN-2b. In 29 patients treated with IFN alpha-2b, HBV DNA pre core mutation were detected… CONTINUE READING