[A new mechanism of tumor resistance to the immune system, based on tryptophan breakdown by indoleamine 2,3-dioxygenase].

Abstract

T lymphocytes represent the main effectors of the immune response that can lead to tumor rejection, which represents the aim of various approaches of immunotherapy that are currently tested. However, in many cases, tumor cells appear to resist immune rejection. We have recently uncovered a new mechanism of tumoral immune resistance based on the expression… (More)

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Cite this paper

@article{Eynde2003ANM, title={[A new mechanism of tumor resistance to the immune system, based on tryptophan breakdown by indoleamine 2,3-dioxygenase].}, author={B J van den Eynde}, journal={Bulletin et memoires de l'Academie royale de medecine de Belgique}, year={2003}, volume={158 7-9}, pages={356-63; discussion 364-5} }