[A new dementia group caused by TDP-43 abnormality].


The TAR DNA-binding protein Mr 43 kDa (TDP-43) is a major component of the tau-negative and ubiquitin-positive inclusions that characterize amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration, which is now referred to as FTLD-TDP. Concurrent TDP-43 pathology has been reported in a variety of other neurodegenerative disorders such as… (More)


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@article{Arai2011AND, title={[A new dementia group caused by TDP-43 abnormality].}, author={Tetsuaki Arai and Masato Hosokawa and Masato Hasegawa and Haruhiko Akiyama and Takashi Asada}, journal={Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica}, year={2011}, volume={113 6}, pages={574-83} }