[A new approach to the synthesis of enzyme inhibitors].

@article{Kritsyn1975ANA,
  title={[A new approach to the synthesis of enzyme inhibitors].},
  author={A M Kritsyn and Sergey N Mikhailov and V. L. Florent'ev},
  journal={Molekuliarnaia biologiia},
  year={1975},
  volume={9 1},
  pages={121-5}
}
On the basis of the application of transition-state theory to enzymatic catalysis a novel approach to the synthesis of inhibitors of enzymes involving conformational rigid substrate has been proposed. It is predicted that the substrates which resemble the natural species in the structure of functional groups, but posses conformational flexibility, will be… CONTINUE READING