• Corpus ID: 24238395

[A new Russian combined antihypertensive preparation proxopheline in the treatment of glaucoma].

@article{Egorov1998ANR,
  title={[A new Russian combined antihypertensive preparation proxopheline in the treatment of glaucoma].},
  author={E A Egorov and T V Stavitskaia},
  journal={Vestnik oftalmologii},
  year={1998},
  volume={114 3},
  pages={
          3-4
        }
}

• E. Egorov, T. V. Stavitskaia
• Published 1998
• Medicine
• Vestnik oftalmologii

Tolerance and efficacy of a new combined antiglaucoma drug proxopheline (1% proxodolol and 0.25% clopheline) is assessed. Studies in 43 patients (63 eyes) with open-angle glaucoma showed that a single instillation of the drug decreases intraocular pressure in 1 h and in 93% of patients the hypotensive effect persists for up to 24 h. Prolonged (4 weeks) use of proxopheline resulted in normalization of intraocular pressure in 90% of treated eyes. The main side effect was dryness in the mouth (30%). The hypotensive effect of proxopheline is superior to that of proxodolol, but it involves a higher incidence of side effects, caused by clopheline--another component of proxopheline.