[A guinea pig model of respiratory syncytial virus infection for cough and its neurogenic inflammatory mechanism].

@article{Ye2011AGP,
  title={[A guinea pig model of respiratory syncytial virus infection for cough and its neurogenic inflammatory mechanism].},
  author={Xin-min Ye and Nan-shan Zhong and Chun-li Liu and Jin Zhao and Sheng Qin and Ru-chong Chen},
  journal={Zhonghua yi xue za zhi},
  year={2011},
  volume={91 24},
  pages={1708-12}
}
OBJECTIVE To establish a guinea pig model of acute and postinfectious cough caused by respiratory syncytial virus (RSV) infection and investigate the role of neurogenic inflammation in its pathogenesis. METHODS Fifty guinea pigs were randomly divided into control group and four groups of Days 6, 12, 28 and 42 after RSV inoculation (n = 10 each). The RSV suspension was inoculated by intranasal instillation. Buxco system was used to assess the cough reflex sensitivity (CRS) to inhaled capsaicin… CONTINUE READING