[3H]prazosin binding to central nervous system regions of male and female rats.

@article{Ambrosio19843HprazosinBT,
  title={[3H]prazosin binding to central nervous system regions of male and female rats.},
  author={Emilio Ambrosio and Mar{\'i}a T Montero and Inmaculada Fern{\'a}ndez and M C Azuara and Luis M. Orensanz},
  journal={Neuroscience letters},
  year={1984},
  volume={49 1-2},
  pages={193-7}
}
Membranes were obtained from the pituitary gland and 13 cerebral regions of male rats and of females during two endocrinological states (estrous and diestrous-1), and assayed for alpha 1-receptor binding, using [3H]prazosin. At two [3H]prazosin concentrations, one near its binding dissociation constant and the other at a value at which the plateau was reached in the binding saturation curve (0.2 and 1.2 nM respectively), [3H]prazosin binding was highest to the frontal cortex, lowest to the… CONTINUE READING