[3H]ketanserin labels serotonin 5-HT2 and alpha 1-adrenergic receptors in human brain cortex.

Abstract

The binding of [3H]ketanserin and [125I]BE 2254 [( beta-(4-hydroxyphenyl)ethylaminomethyl]tetralone) was characterized in human brain cortex membranes. As observed in saturation experiments, [3H]ketanserin (a reportedly selective serotonin 5-HT2 ligand) and [125I]BE 2254 (a selective alpha 1-adrenergic antagonists) labeled, apparently, a homogeneous class… (More)

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Cite this paper

@article{Hoyer19873HketanserinLS, title={[3H]ketanserin labels serotonin 5-HT2 and alpha 1-adrenergic receptors in human brain cortex.}, author={D. Hoyer and Paul Vos and Annemarie Closse and Jos{\'e} Palacios and G. Engel and H. Davies}, journal={Journal of cardiovascular pharmacology}, year={1987}, volume={10 Suppl 3}, pages={S48-50} }